HPV infection is a viral infection. There are more than 100 types of human papillomavirus (HPV). Some types of HPV infection cause skin growths called warts and some types of HPV infection can cause cancer.
Most HPV infections don't lead to cancer. But some types of genital HPV can cause cancer of the lower part of the uterus that connects to the vagina, called the cervix. Other types of cancers have been linked to HPV infection. These include cancers of the anus, penis, vagina, vulva and back of the throat. Cancer at the back of the throat is called oropharyngeal cancer.
These infections are often passed through sex or through other skin-to-skin contact. Vaccines can help protect against the strains of HPV most likely to cause genital warts or cervical cancer.
Usually, the body's immune system defeats an HPV infection before it creates warts. Different types of HPV produce different warts, including:
Genital warts. Some appear flat. Others look like small cauliflower-like bumps or tiny stemlike bumps. In women, genital warts appear mostly on the vulva. But they also can occur near the anus, on the cervix or in the vagina.
In men, genital warts appear on the penis and scrotum or around the anus. Genital warts rarely cause discomfort or pain. But they might itch or feel tender.
HPV infections cause almost all cervical cancers. But cervical cancer may take 20 years or longer to develop after an HPV infection. The HPV infection and early cervical cancer typically don't cause symptoms. Getting vaccinated against HPV infection is the best way to protect against cervical cancer.
Because early cervical cancer doesn't cause symptoms, it's vital that women have regular screening tests. These tests can find changes in the cervix that might lead to cancer. Current guidelines recommend that women ages 21 to 29 have a test that checks cervical cells for cancer, called a Pap test, every three years.
Women ages 30 to 65 are advised to keep having Pap tests every three years. Or the Pap test can be every five years for women who also get an HPV DNA test at the same time. Women over 65 can stop testing if they've had three regular Pap tests in a row, or two HPV DNA and Pap tests with no irregular results.
If you or your child has any warts that cause embarrassment, discomfort or pain, seek advice from your healthcare professional.
HPV infection occurs when the virus enters the body, usually through a cut or other damage to skin. The virus spreads mainly by skin-to-skin contact.
Genital HPV infections are contracted through having sex, anal sex and other skin-to-skin contact of the genitals. Some HPV infections spread through oral sex.
People who are pregnant and have an HPV infection with genital warts can give the infection to the baby. Rarely, the infection may cause a noncancerous growth in the baby's voice box, called the larynx.
Warts spread easily. This means that warts are contagious and can spread through direct contact with a wart. Warts also can spread by touching something that has touched a wart.
HPV infections are common. Risk factors for HPV infection include:
It's hard to prevent HPV infections that cause common warts. If you have a common wart, you can prevent the spread of the infection and keep new warts from forming by not picking at a wart and not biting your nails.
To lower the risk of contracting HPV infections that cause plantar warts, wear flip-flops or other shoes on public pool decks and in locker rooms.
Lower the risk of getting genital warts and other HPV-related genital sores by:
Gardasil 9 is an HPV vaccine approved by the U.S. Food and Drug Administration and can be used for males and females to protect against cervical cancer and genital warts.
The vaccine works best if a person gets it before having the first sexual contact. Once someone has HPV, the vaccine might not work as well or at all. Also, younger people respond better to the vaccine than older people do. If given before someone has HPV infection, the vaccine can prevent most cervical cancers.
Two doses of the HPV vaccine are recommended for children age 11 and 12, but this vaccines can be given as young as 9 years of age. The two-dose series is given until age 14. The doses are given at least five months apart. Teens and young adults who begin the vaccine series at ages 15 through 26 should get three doses of the vaccine.
A healthcare professional might be able to diagnose HPV infection by looking at the warts.
If genital warts don't show, one or more of the following tests can find them:
Warts often go away without treatment, particularly in children. But there's no cure for the virus. So the warts can come back in the same place or other places.
Medicines to get rid of warts usually go directly on the warts. These medicines might need to be used many times before the warts go away. Examples include:
If medicines don't work, one of these methods can remove warts:
A procedure called a colposcopy can remove HPV from the cervix. A healthcare professional uses a tool, called a coloscope, to see the cervix and take tissue samples, called a biopsy, of areas that look atypical.
Precancerous lesions need to be removed. Options include freezing, called cryosurgery, and laser surgical removal. Another method called loop electrosurgical excision procedure (LEEP) uses a thin looped wire charged with an electric current to remove a thin layer of a section of the cervix. And cold knife conization is a surgical procedure that removes a cone-shaped piece of the cervix.
You'll likely start by seeing your main healthcare professional. Depending on where your warts are, you may be referred to a specific healthcare professional. For example, you may be referred to a specialist who treats skin, called a dermatologist; a specialist who treats feet, called a podiatrist; or a reproductive organs specialist, either a gynecologist or urologist.
Here's some information to help you get ready for your appointment.
Before your appointment, make a list of:
For HPV infection, questions to ask include:
Don't hesitate to ask all the questions you have about HPV infection.
Your healthcare professional is likely to ask you questions, such as: